One more Alzheimer's drug fails in early-onset disease studyFebruary 10, 2020 - 13:01 AMT PanARMENIAN.Net - Roche’s experimental drug gantenerumab failed to slow cognitive decline in people with a rare inherited form of Alzheimer’s disease, the latest setback for companies hunting for a cure for the devastating brain-wasting disease, Reuters reports. The study focused on autosomal dominant Alzheimer’s disease, caused by gene mutations in which those afflicted typically develop Alzheimer’s disease before the age of 60 and have a 50-percent chance of passing the mutation on to their children. Roche said the failure in the study being conducted by scientists at Washington University in St. Louis will not impact two additional late-stage studies of gantenerumab in people with common form of Alzheimer’s disease that is not directly caused by gene mutations. Like many other Alzheimer’s prospects, gantenerumab is designed to bind to and remove beta-amyloid plaques that are seen as a driver behind brain cell death. Pursuit of a successful treatment for Alzheimer’s has been marked by more than 100 failures, though companies including Roche continue to push ahead with potential medicines in hopes of eventually taming a condition that affects nearly 6 million Americans and is growing more prevalent as the population ages. Top stories Authorities said a total of 192 Azerbaijani troops were killed and 511 were wounded during Azerbaijan’s offensive. In 2023, the Azerbaijani government will increase the country’s defense budget by more than 1.1 billion manats ($650 million). The bill, published on Monday, is designed to "eliminate the shortcomings of an unreasonably broad interpretation of the key concept of "compatriot". The earthquake caused a temporary blackout, damaged many buildings and closed a number of rural roads. Partner news | Cyprus parliament honors Armenian genocide victims Acting House President Zacharias Koulias noted that April 24 marks the “black anniversary” of the Armenian genocide. Armenia PM, France envoy discuss regional matters Issues related to the consistent development of Armenia-France cooperation were discussed. Azerbaijan razes historic Armenian church to ground Azerbaijan has demolished the historic Armenian Church of St. John the Baptist (known as Kanach Zham). Russia to begin assessing migrant workers' speaking skills Rosobrnadzor is planning to change the Russian language exam for migrant workers and include an assessment of speaking skills |