Researchers discover drug that helps get rid of fat: reportJanuary 8, 2018 - 16:55 AMT PanARMENIAN.Net - According to a new study, scientists may have discovered a drug that could get rid of fat without recourse to dieting, TheCable Lifestyle says. The drug was found to significantly reduce body weight and blood cholesterol levels without reducing food intake. The team of researchers at the University of Texas Medical Branch (UTMB), Galveston focused on the inhibition of nicotinamide-N-methyltransferase (NNMT), an enzyme which is believed to play a role in slowing fat cell metabolism. Mice treated with the NNMT inhibitor were said to have experienced a 30 percent reduction in the size of their white fat cells, and a 7 percent reduction in total body weight. The researchers say they were able to “shrink” fat cells in obese mice fed a high-fat diet by using small molecules to block the NNMT. Stanley Watowich, senior study author, said the findings indicate that inhibiting NNMT could be a way of tackling obesity. Explaining the research, Watowich said: “As fat cells grow larger, they begin to overexpress a protein that acts as a metabolic brake that slows down fat cell metabolism, making it harder for these cells to burn accumulating fat. “In addition, as the fat tissue expands, they secrete greater amounts of hormones and pro-inflammatory signals that are responsible for several chronic diseases, including type 2 diabetes and cardiovascular disease.” The result of the study was published in the journal Biochemical Pharmacology. Top stories Authorities said a total of 192 Azerbaijani troops were killed and 511 were wounded during Azerbaijan’s offensive. In 2023, the Azerbaijani government will increase the country’s defense budget by more than 1.1 billion manats ($650 million). The bill, published on Monday, is designed to "eliminate the shortcomings of an unreasonably broad interpretation of the key concept of "compatriot". The earthquake caused a temporary blackout, damaged many buildings and closed a number of rural roads. Partner news | Czech-Armenian military cooperation discussed in Yerevan A delegation led by the Director General for the Industrial Cooperation Division of the Ministry of Defence of the Czech Republic visited Armenia. U.S. welcomes efforts to define Armenia-Azerbaijan border The United States welcomes efforts to define the border between Armenia and Azerbaijan, says Vedant Patel. Biden honors resilience of Armenian people on April 24 U.S. President Joe Biden has issued a statement on the 109th anniversary of the Armenian Genocide. Ex-Karabakh leader moved to solitary confinement cell in Baku, his son says David Vardanyan is the son of former Karabakh leader Ruben Vardanyan who who is currently imprisoned in Azerbaijan. |