Why HIV-infected patients suffer higher cancer ratesDecember 6, 2018 - 15:08 AMT PanARMENIAN.Net - AIDS patients suffer higher rates of cancer because they have fewer T-cells in their bodies to fight disease. But new research examines why HIV-infected patients have higher rates of cancer--among the leading causes of death among that population--than the general population, Technology Networks says. Researchers at Case Western Reserve University's School of Dental Medicine, who lead the study, published their results in Nature Communications, highlighting how T-cells move, multiply and invade other cells in HIV-infected patients. "The cells in question release exosomes into the blood stream--think small nanoparticles--that don't cause cancer, but they support it," said Ge Jin, associate professor of biological sciences at the School of Dental Medicine and the study's author and principal investigator. "In other words, the cancer grows faster and more aggressively in patients with HIV." Compared with the general population, people infected with HIV are: - 500 times more likely to be diagnosed with Kaposi sarcoma; - 12 times more likely to be diagnosed with non-Hodgkins lymphoma; - and, among women, three times more likely to be diagnosed with cervical cancer, according to the National Cancer Institute. "There are big implications here," Jin said. In addition to being linked to an increased risk of cancer, HIV-infected patients are more likely to die of other type of cancer, including lung cancer and cancer in the head and neck, than uninfected people with the same cancers. Researchers studied more aggressive cells in head and neck cancer cases related to 18 HIV-infected patients--12 of them from Cleveland. In a nutshell, exosomes played a big role in altering the growth and spread of cancer cells in the patients studied, Jin said. "They assist in a way we hadn't--until now--been able to understand," he added. Top stories Authorities said a total of 192 Azerbaijani troops were killed and 511 were wounded during Azerbaijan’s offensive. In 2023, the Azerbaijani government will increase the country’s defense budget by more than 1.1 billion manats ($650 million). The bill, published on Monday, is designed to "eliminate the shortcomings of an unreasonably broad interpretation of the key concept of "compatriot". The earthquake caused a temporary blackout, damaged many buildings and closed a number of rural roads. Partner news | Scholz hopes Armenia-Azerbaijan peace treaty will be signed this year German Chancellor Olaf Scholz hopes that a peace treaty between Armenia and Azerbaijan will be signed this year. Ucom equips four bus stops in Ijevan with free Wi-Fi Ucom now provides free Wi-Fi coverage in smart bus stops in four communities of Ijevan. Armenia, Russia discuss life extension of Metsamor nuclear plant Issues regarding the extension of life of the 2nd power unit of the Armenian Nuclear Power Plant were discussed in Yerevan. Armenians stage more campaigns against territorial concessions to Azerbaijan Protesters blocked more roads across Armenia on Friday, April 26 in continuing attempts to scuttle territorial concessions to Azerbaijan. |